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Projects

Depyrogenation Oven

Brief

Labec were commissioned to build a High Temperature Depyrogenation Oven to sterilise glass vials for a pharmaceutical company. The oven has a pass through construction between ‘dirty’ and ‘clean’ rooms. The oven can sterilise up to 10,000 large glass vials at a time. The Depyrogenation process heats the glass vials to a temperature of 280ºC in a sterile environment. Unsterilised vials are placed into the oven. After the ‘dirty’ side doors are closed the sterilisation process can be started. Once sterilised the ‘clean’ doors can be opened to complete the bottling process. Access doors are interlocked to maintaining sterile integrity between the dirty and clean rooms and protect users against the hot surfaces. The chamber used horizontal air flow for excellent accuracy at high temperature with a fully loaded chamber.

 

  • 304 stainless steel interior and exterior.
  • Automatic locking doors, by actrator with temperature overrides.
  • Venting duct automatically purge and filter airflow. HEPA filtered air intake controlled by system time, temperature and purity.
  • LAN connection for control and monitoring.
  • Trolley loading and unloading from other side. Loading on the ‘dirty’ side sterilises the glass to the ‘clean’ side for production.
  • Air flow rate to give ±2ºC at 280ºC.
  • Special requirements to allow continuous operation and quick cool down for faster production using cooled filtered air system operated by the control system.